GAP19 TRIFLUOROACETATE SALT

Code: SML1426-1MG D2-231

Application

Gap19 trifluoroacetate salt has been used to inhibit Ca2+/calmodulin (CaM) gating response of connexin 43 (Cx43) gap junctions.

Biochem/p...


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€259.90 1MG
€319.68 inc. VAT
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Application

Gap19 trifluoroacetate salt has been used to inhibit Ca2+/calmodulin (CaM) gating response of connexin 43 (Cx43) gap junctions.

Biochem/physiol Actions

Gap19, nonapeptide from the cytoplasmic loop of Connexin-43, is a selective blocker of connexin 43 (Cx43) hemichannel that does not block GJ or Cx40/Panx-1 channels in cardiomyocytes and astrocytes. Gap19 prevents Cx43 hemichannel opening and protect against myocardial ischemia/reperfusion injury.

Packaging

1 mg in glass bottle

assay≥95% (HPLC)
colorwhite to off-white
formpowder
Quality Level100
shipped inwet ice
storage temp.−20°C
Cas Number1507930-57-5
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